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Analyst
Coagulation disorders
The tests allow us to detect the causes of spontaneous bruising, burst blood vessels.
- Prothrombin time (PT)
- Kaolin-Kefalin Time (APTT)
- Fibrinogen
Prothrombin time (PT)
Prothrombin time (PT) is one of the tests of the coagulation system, indicating a possible deficiency of factor VII or vitamin K. Abnormal values occur in kidney disease, in the absence of coagulation factors.
Kaolin-Kefalin Time (APTT)
The kaolin-kefalin time (APTT) is a sensitive review test used to assess coagulation. A prolonged time is indicative of deficiency of individual coagulation factors, heparin/hirudin treatment, acquired lupus anticoagulant. A shortened time may be an expression of hypercoagulability.
Fibrinogen
Fibrinogen is formed in the liver and is involved in clot formation. Increased values occur during menstruation, pregnancy, nephrotic syndrome, glomerulonephritis, trauma, collagenoses (lupus erythematosus, periarteritis nodosa), it is also a risk factor for ischaemic heart disease. Decreased values may occur in congenital fibrinogen deficiency, liver disease, DIC, acute promyelocytic leukaemia, cancer, infectious mononucleosis.
