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NeoBon studies

NeoBona is a new generation screening test for non-invasive prenatal diagnosis. It detects the most common chromosomal aberrations occurring during pregnancy by analysing foetal DNA present in the mother's blood. It uses the so-called "fetal fraction", which ensures greater precision than other tests available on the market.

Using the latest technology in DNA sequencing, neoBona has a sensitivity of over 99% in detecting Down Syndrome and Patau Syndrome and over 97% in Edwards Syndrome.

The test can be carried out on women who are at least 10 weeks pregnant, both singleton and twin pregnancies, and also in the case of in vitro fertilisation. On request of the pregnant woman, the examination can determine the sex of the foetus from the 10th week.

Types of tests:

Scope: Trisomy 21, 18 and 13 with the optionto determine the sex of the fetus*

* In the case of a twin pregnancy, if the "sex of the fetus" option is selected, the presence of a Y chromosome is determined. When a Y chromosome is detected, it is determined that at least one of the two fetuses is male. This does not analyse changes in the sex chromosomes.
1800.00 zł
neoBona Advanced
Scope: Trisomy 21, 18 and 13 + fetal sex + changes in number of sex chromosomes: Turner syndrome (45,X), Klinefelter syndrome (47, XXY)
1800.00 zł

Thetest requires a referral - a questionnaire, which can be collected by the patient at a doctor's appointment in a gynaecologist's surgery, registration, in a treatment room (Luxmed facilities - Radziwiłłowska and Koncertowa).

Waiting time for the result - 16 working days.

Theresult of the test - should be interpreted by the doctor in charge of the pregnancy.

Who should consider taking the test

  • Women who wish to have a non-invasive test for fetal trisomy 21, 18 and 13 and gender-specific genetic defects (Turner's syndrome, Klinefelter's syndrome) can also identify the sex of the baby.
  • Women over the age of 35 who do not wish to opt for invasive prenatal testing.
  • Women whose biochemical and ultrasound findings in the first and second trimester of pregnancy suggest a high risk of chromosomal aneuploidy.
  • Women who have contraindications to invasive prenatal testing, such as placenta previa, high risk of miscarriage, HBV or HIV infection, etc.
  • Women who have undergone in vitro fertilisation treatment.

Contraindications to the test

  • If the woman has ever undergone stem cell therapy.
  • If the woman has received a blood transfusion within 6 months before becoming pregnant.
  • If the woman has undergone an organ transplant.

What types of chromosome aberrations are detected by the test:

  • A trisomy is caused by the presence of three copies of a chromosome instead of the standard two. neoBona detects the following trisomies:
    - Trisomy 21 called Down Syndrome, is the most common trisomy.
    - Trisomy 18 called Edwards Syndrome, has a high incidence of miscarriage and a high mortality rate.
    - Trisomy 13 called Patau Syndrome, is also associated with a high risk of miscarriage and high mortality.
  • Sex chromosome changes - neoBona detects changes in the number of sex chromosomes, including:
    - Turner syndrome (45, X), lack of a second copy of the X chromosome in girls.
    - Klinefelter syndrome (47, XXY), the presence of an extra copy of the X chromosome in boys.

Read more:

info luxmedThe examinations are performed in the facility at 5 Radziwiłłowska Street and 4D Koncertowa Street. In order to make an appointment, please contact
with the Patient Services Office - tel. 81 532 37 11.